APP and neuroblastoma: As an acute in vitro model, mouse neuroblastoma cells (N2a-APP/Swe) were exposed to nPM; pro-amyloidogenic APP processing was assessed as the ratio (sAPPβ/α) of soluble fragments from β-secretase (sAPPβ, pro-amyloidogenic) and α-secretase (sAPPα, non-amyloidogenic).