The 10-week HF feeding trial did not change body or liver weight (Fig. 2A,B), triglycerides (TG) concentrations in liver, muscle and adipose tissue (Fig. 2D); or plasma activities of aspartate aminotransferase (AST), alanine aminotransferase (ALT) (Fig. 2E), TG, total cholesterol (TC), FFA, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) (Fig. 2F), but it did significantly increase the quantity of mesenteric fat (Fig. 2C) and plasma malondialdehyde (MDA) concentration (Fig. 2F). The gene discussed is GPT; the disease is hydrops fetalis.