On the other hand, we analyzed the relationship between NRIP2 expression and colorectal cancer molecular typing in 565 cases of colorectal cancer from a global cDNA expression genechip database and found that high NRIP2 expression was closely related to the C4-cancer stem cell (CSC) subtype of colorectal cancer (Fig. 2h) [29]. The gene discussed is NRIP2; the disease is cancer.