NFKB1 and leukemia: Resveratrol can inhibit growth and induce apoptosis in several human cancer cells, including mouse and human leukemia cell lines, through various mechanisms such as; modulating nitric oxide production, accumulation of p53 and p21, inhibition of ribonucleotide reductase and DNA polymerase, inducing arrest at the S and G2 phases of the cell cycle and inhibiting interleukin-1β–induced activation of NF-κB [101].