PTK2 and cancer: These observations are also consistent with the well-recognized signaling or functional role of FAK or Myc across a spectrum of human cancer.17, 39 However, it is still intriguing that neither of these pathways appears to be affected by VS-6063 or JQ1 in the VS-6063-resistant SK-OV-3 cells (Figure 7), despite a strong effect on cell viability.