The area under the receiver-operator characteristic curve (AUC) of PSA-Gi predicting PCa in any concentration range of total PSA (0.795, 95% CI; 0.753–0.837 and 0.752, 95% CI; 0.690–0.813, respectively) was much higher than those of PSA-Gi/total PSA (0.734, 95% CI; 0.686–0.782 and 0.718, 95% CI; 0.659–0.779, respectively) and total PSA (0.638, 95% CI; 0.586–0.691 and 0.550, 95% CI; 0.483–0.618, respectively) (Table 2, Figure 3c,f). This evidence concerns the gene KLK3 and posterior cortical atrophy.