HSPA5 and neuroblastoma: RECK and GRP78 were shown to colocalize in the cytoplasm and perinuclear area in neuroblastoma cells, indicating that RECK and GRP78 are colocalized in the ER because the glycosylphosphatidylinositol-anchored RECK is transported from the ER to the plasma membrane through the Golgi apparatus [16,34].