CCL22 and Alzheimer disease: Also, the mRNA levels of TSLP-regulated Th2-type chemokines including macrophage-derived chemokine (MDC) and thymus and activation-regulated chemokine (TARC) as well as proinflammatory cytokines such as IL-6 were found to be decreased in the skin lesions from dTBP2-treated AD mice (Figure 4).