MMP1 and neoplasm: We also identified a significant increase in MMP‐1 which drives the invasive behaviour, intravasation and metastatic dissemination of tumour cells (Juncker‐Jensen et al., 2013), with an increased expression linked to lymphatic invasion and lymph node metastasis (Kessenbrock et al., 2010) as well as invasion and migration, with its inhibition significantly decreasing tumour growth and metastasis in vivo (Pulukuri and Rao, 2008).