ERVW-1 and HIV infectious disease: Thus, for example, superinfection occurs unhindered by HIV envelope protein (Env)‐specific antibodies,1 the majority of which are non‐neutralizing.2 However, given that the mechanism of viral protection and clearance by antibodies in vivo is so widespread, we, and others, have studied humoral responses in HIV‐infected donors for more than two decades to understand how to prevent and control HIV infection.