MC4R and gestational diabetes: In this regard, the aim of this study was to investigate the relationship between clinical parameters in GDM and variants in genes involved with nutrients and metabolism (namely, TCF7L2, PPARG2, PPARGC1A, carbohydrate metabolism; FTO, MC4R, APOA5, LDLR, GCKR, fat metabolism; MTHFR, folate metabolism).