For example, Chromosome 8 Open Reading Frame 4 (C8orf4), ranked 9th by NMF, was identified as “Thyroid cancer 1 (TC1)” (Panebianco et al., 2015; Zhang et al., 2015; Zhu et al., 2015; Huang et al., 2016). Here, TCIM is linked to thyroid gland carcinoma.