HT1080 fibrosarcoma cells, which adhere to laminin-111 and E8 using integrin α6β1 (Brown and Goodman, 1991, Deutzmann et al., 1990), adhered equally well to mini-E8, and cell adhesion was abrogated by mutation of the critical integrin-binding residue, γ1 E1605Q (Figure 1C). Here, LAMB2 is linked to fibrosarcoma.