The information regarding mTOR signaling in Pompe muscle cells is limited to a recent finding of reduced insulin‐stimulated mTORC1 activation in two cellular models of Pompe disease—GAA‐knockdown C2C12 myoblasts and GAA‐deficient human fibroblasts from infantile Pompe patients (Shemesh et al, 2014). Here, MTOR is linked to glycogen storage disease II.