MTOR and inclusion body myopathy with Paget disease of bone and frontotemporal dementia: The disturbance of mTOR signaling in Pompe muscle cells is reminiscent of that found in muscle from a mouse model of IBMPFD/ALS (inclusion body myopathy associated with Paget's disease of the bone, frontotemporal dementia, and amyotrophic lateral sclerosis; Ching et al, 2013).