Furthermore, the late‐onset myopathy described in muscle‐specific TSC knockout mice was linked to the mTOR‐dependent inhibition of autophagy through ULK1, and the pathology was reminiscent of that in autophagy‐deficient muscle (Bentzinger et al, 2013; Castets & Ruegg, 2013). This evidence concerns the gene TSC1 and myopathy.