When analyzing chemotherapy efficacy in the correlation of the expression level of CMTM1_v17, patients with low CMTM1_v17 expression in the tumor tissues after NAC suggested higher PR rates than those with high CMTM1_v17 expression, which were confirmed in 78 NSCLC patients who have received NAC. Here, CMTM1 is linked to non-small cell lung carcinoma.