LGALS3 and Parkinson disease: Furthermore our previous studies showed that: (i) galectin-3 is involved in the proinflammatory response triggered by α-synuclein in microglial cells24, a hallmark of Parkinson’s disease physiopathology, and (ii) mice lacking galectin-3 were more resistant to hippocampal degeneration in a model of global cerebral ischemia that mimics the brain damage caused by cardiac arrest22.