Several studies indicate that DDRGK1 forms a large protein complex with UFL1/NLBP (Ufm1-specific ligase 1), the putative tumour suppressor C53/LZAP and Ufm1 (ubiquitin-fold modifier 1) and each of these proteins is involved in ufmylation12, 14, 15, 16. The gene discussed is UFL1; the disease is neoplasm.