Using Ly6C as a marker to distinguish resident versus inflammatory macrophages, we observed an increased percentage of inflammatory Ly6Chi macrophages and reduced percentage of resident Ly6Clo macrophages in Klrk1+/+ versus Klrk1−/− mice resulting in a predominance of inflammatory macrophages within the tumour (Fig. 7c,d). Here, KLRK1 is linked to neoplasm.