= 0.27), which includes the risk allele C for rs5743314, was statistically associated with the risk of progression to end-stage HCV-related liver diseases (p value = 0.0248), despite the absence of any correlation with the two other TLR3 SNPs (rs1879026 and rs5743313) with risk for HCV infection or end-stage liver disease (Table 6). The gene discussed is TLR3; the disease is liver disorder.