Similarly, haplotype analysis was performed between patients with chronic HCV and patients diagnosed with liver cirrhosis and HCC, revealing that one out of three haplotypes was close to becoming significant, which includes the three TLR3 SNPs rs1879026-G, rs5743313-T, and rs5743314-C, with a p value = 0.0632 (Table 7, Figure 1). This evidence concerns the gene TLR3 and hepatocellular carcinoma.