The BL patients presented with higher risk features as compared with DLBCL patients in terms of numbers of extranodal disease (P = 0.004) and poor ECOG score (P = 0.038), while age (P = 0.151), gender (P = 0.692) and CD4 cell count (P = 0.526) were distributed equally in the two groups. This evidence concerns the gene CD4 and Burkitt lymphoma.