For example, clinical studies have demonstrated overexpression of CACNA1D (Cav1.3) (L type), CACNA1A (Cav2.1) (P/Q type), and CACNA1G (Cav3.1) (T type) in lung cancer, and overexpression of CACNA1A (Cav2.1) was associated with poor prognosis [15]. The gene discussed is CACNA1A; the disease is lung cancer.