The group of children and adolescents with T1DM had significantly higher HbA1c levels (P = 0.005), higher C-reactive protein levels (P = 0.003), higher IL12 levels (P = 0.003), and higher C. albicans IgG antibody level (P = 0.049) versus control subjects. The gene discussed is CRP; the disease is type 1 diabetes mellitus.