ROR2 and osteosarcoma: Examining BT549 (breast cancer) and U2OS (osteosarcoma) cells as examples, which are also non-ciliated (Supplementary Fig. 3a), we first confirmed that siRNA against either Ror2 or IFT20 (Supplementary Fig. 3b) also reduced the invasiveness of these tumor cells (Supplementary Fig. 3e).