As endometriosis is a chronic inflammatory disorder where the immune surveillance is impaired due to local production of pro-inflammatory cytokines including TNF-alpha, IL-1, IL-6 and IL-8 and partially originating from ectopic lesions stromal cells [35], we propose that DAPK1 in endometriotic stroma may be involved in cellular processes associated with immunity. This evidence concerns the gene CXCL8 and endometriosis.