S100A8 and gastric cancer: Thereafter, logistic regression analysis was performed and the results show that vacA i1m1 and vacA i1m2 genotypes were strongly associated with the risk of GC, the Odds Ratio (95% confidence interval) was 29.73 [5.08–173.73]) and 9.17 [2.06–40.82] respectively while vacAs1/cagA+ seem to be more associated to DU since it’s less present in GC cases, (OR: 0.13 [0.02–0.75] when compared with DU group “Table 6”.