In a cross-sectional study of obese metabolic syndrome patients (Gene Expression Omnibus (GEO) dataset GSE28070 analyzed using GEO2R)[43] we observed a significant difference in S100A8 and S100A9 expression in adipose tissue from individuals with low habitual n-3 PUFA intake (<1g/day, n = 6) vs. high habitual intake (>2g/day, n = 6). This evidence concerns the gene S100A8 and metabolic syndrome.