There is far less known about BLT2 in immunoregulation compared to BLT1, however there is increasing evidence to suggest a prominent role of these receptors in a number of different aspects of cancer development, such as proliferation, survival, angiogenesis and Ras-induced transformation and metastasis, further indicating the relevance of 5-LO metabolites and accompanying receptors as molecular therapeutic targets [67,68,69,70]. The gene discussed is ALOX5; the disease is cancer.