In respect to cancer, studies have shown that 1,25(OH)2D3 induces the expression of anti-proliferative and pro-apoptotic genes such as p21, p27, and BAX, and decreases the expression of oncogenic transcription factors like MYC and Hypoxia-Inducible factor 1-α (HIF1α) [3]. This evidence concerns the gene HIF1A and cancer.