Indeed, human mutations within the SLC16A1 (MCT-1) promoter which increased its expression were found in families suffering from exercise-induced hyperinsulinemia (EIHI) (Otonkoski et al., 2007), revealing the importance of the absence of this transporter from β-cell for normal insulin secretion. The gene discussed is SLC16A1; the disease is exercise-induced hyperinsulinism.