However, we also observed that the CAD/MI GWAS SNP at this locus, rs17087335, is in tight LD with lead trans-eQTLs targeting expression of trans-eGenes GDAP1 (ganglioside induced differentiation associated protein 1 on chr 8; P < 1E-20) and CACNA1E. (calcium voltage-gated channel subunit alpha1 E on chr 1; P < 1E-7, Additional file 1: Table S12). This evidence concerns the gene CACNA1E and coronary artery disorder.