A small study of 39 Japanese men also noted that those with versus without MetS had higher prevalence of CAD (31.3 versus 4.3%, p = 0.033) and lower serum adiponectin levels (4.5 ± 0.6 versus 6.4 ± 0.6 μg/mL, p = 0.014) [48]. This evidence concerns the gene ADIPOQ and metabolic syndrome.