However, the expression levels of other hormone receptors related to the hypothalamic-pituitary-gonadal axis (androgen receptor (AR), follicle-stimulating hormone receptor (FSHR), luteinizing hormone receptor (LHR) and gonadotropin-releasing receptor (GnRHR)) in LGSC, which could also mediate the effects of steroid hormones on the development and progression of ovarian cancer, have not been shown. The gene discussed is LHCGR; the disease is ovarian cancer.