NFKB1 and cancer: Previous reports indicated that NF-κB is involved in multiple cancer-related processes by either promoting proliferation or suppressing apoptosis and stimulating EMT and angiogenesis, which facilitates distant metastasis [66] Our results suggest that the metastatic influence of NF-κB is mediated via the invasion enhancing abilities of miR-182, whereas in contrast, proliferation is not effected.