HOTAIR and breast cancer: Examples include reports of lncRNA-HOTAIR in ER-induced tamoxifen resistance in breast cancer [25], lncRNA-UCA1 in cisplatin-based resistance in ovarian cancer cells [26], LncRNA-AK022798 in cisplatin-based drug resistance in gastric cancer cells [27] and H19 and lncRNA-ROR in hepatocellular carcinoma cells [4].