Similar to Bmi-1, Sall4 expression has been reported in numerous hematological malignancies, including myelodysplastic syndromes [48], AML [49, 50], chronic myelogenous leukemia [51] and precursor B cell lymphoblastic lymphoma [52, 53]. This evidence concerns the gene BMI1 and chronic myelogenous leukemia, BCR-ABL1 positive.