Notably, the patient failed on three prior regimens before enrollment into the LY2874455 (pan-FGFR inhibitor) trial, wherein the patient, whose tumor was characterized as exhibiting FGFR2 protein overexpression by IHC as well as high-copy-number FGFR2 amplification, responded for over 1 year. Here, FGFR2 is linked to neoplasm.