We also measured the levels of two cellular proliferation antigens, Ki67 and PCNA, in tumor tissues from the xenografts via IHC and found that the expression levels of both of these antigens were significantly stronger in theSMMC-7721-CBX6cell xenografts than in theSMMC-7721-NC cell xenografts (Supplementary Figure 4A).In contrast, the expression levels of Ki67 and PCNA were significantly lower in the HCCM3-CBX6i cell xenografts than in the HCCLM3-NCcell xenografts (Supplementary Figure 4B). The gene discussed is PCNA; the disease is neoplasm.