Furthermore, multivariate Cox regression analysis showed that CBX6 expression levels, vascular invasion, the presence of HBeAg, and the presence of HBsAg were independent risk factors for HCC recurrence and that CBX6 expression levels, the presence of HBeAg, and the presence of HBsAg were independent risk factors for OS in HCC patients (Table 2). The gene discussed is CBX6; the disease is hepatocellular carcinoma.