AKT1 and cancer: The main canonical pathways detected by IPA and confirmed by KOBAS 2.0 revealed enrichment of the Human Embryonic Stem Cell Pluripotency, VEGF signaling, Molecular Mechanisms of Cancer, B Cell Receptor, PDGF, ERBB, Matrix Metalloproteases and PI3K/AKT signaling pathways involving transcripts detected in the integrative analysis (Figure 1C, Table 1).