Currently, there are seventeen genes associated with ARCI: TGM1, ABCA12, ALOXE3, ALOX12B, ALOX15B, NIPAL2, NIPAL4, CYP4F22, PNPLA1, LIPN, NIPA1, NIPA2, CERS3, SLC27A4, SPINKS, LI5 and KRT10 [2–4]. Here, ALOXE3 is linked to autosomal recessive congenital ichthyosis.