Some studies have explored the mechanisms by which thyroid hormone alters calcium metabolism.[2,9] Increased serum ALP level was found in approximately 50% of the patients with hyperthyroidism complicated with hypercalcemia.[2,8,11] Whereas in our case, in spite of the normal ALP level, the bone formation markers (BALP and PINP), and bone resorption marker were all increased. Here, TG is linked to hypercalcemia disease.