GTT analysis revealed that at time zero, aged AAV-GFP mice showed higher insulin levels than their younger AAV-GFP counterparts, 1.56±0.31 ng/mL vs 0.41±0.08 ng/mL respectively (Fig. 6C and Fig. 2D), suggesting the development of age-related hyperinsulinemia. The gene discussed is INS; the disease is Hyperinsulinemia.