Transcriptional analysis of an HD mouse knock-in allelic series11, 12, 13 and a human post-mortem dataset18 did not reveal significant dysregulation of Gm12695 or its human orthologue C1orf87, supporting the finding that abnormal regulation of Gm12695 is a consequence of transgene integration in R6/2. This evidence concerns the gene C1orf87 and Huntington disease.