In the subgroup of patients with genotype information (64 typical AMD, 86 PCV, 1,267 controls), both CFH rs800292 (OR 0.55, p = 0.009) and ARMS2 rs10490924 (OR 2.70, p < 0.001) were significantly associated with nAMD, as were increasing age and past smoking. The gene discussed is CFH; the disease is age-related macular degeneration.