In our study three different patients contained CNVs in genetic regions previously associated with coronary artery calcification in African Americans and carotid intima media thickness over 10 years in Chinese (2q37.3(LOC105373979, LOC728323), 1p22.2 (GBP3) and 10q21.1 (PCDH15))25, 26. The gene discussed is GBP3; the disease is coronary artery calcification.