We found that all parts of the tumour carried the same APC (c.C4099T, p.Q1367*) and TP53 (c.G524A, p.R175H) variants, and no further SNVs in any individual sample in coding regions covered by our panel (confirmed by Sanger and SNuPE validation; see ‘Methods' section). Here, TP53 is linked to neoplasm.