ICAM1 and cancer: In contrast, several articles have reported that upregulated INHBA expression may promote cancer cell proliferation in several cancers, and the level of Activin A in plasma might be associated with cancer progression in clinical [31–34], In addition, intercellular adhesion molecule 1 (ICAM-1) was upregulated in gastric cancers and cancer progression, which were associated with poor prognostic effect [35, 36].