Eosinophils in asthma patients have significantly increased activity compared with eosinophils in healthy people, showing increased expression of outer-membrane integrins, exhibiting overexpression of TGF-β1, having increased adhesive properties, and having stronger effects on inducing gene expression of TGF-β1, WNT-5a, and collagen in ASM cells. This evidence concerns the gene TGFB1 and asthma.