ABCB4 and ovarian carcinoma: ABCB4 was up-regulated 176-fold in doxorubicin- and 147-fold in vincristine-resistant sublines of ovarian cancer cells which proves that ABCB4 does contribute to chemotherapy resistance just like ABCB1 (Duan et al., 2004; Morita and Terada, 2014).