The positive rate of T-Ab in patients carrying CA + AA of -863C > A in the TNF-α promoter region was notably higher in the OMG + TAO group than the patients in the OMG group (P<0.05); the positive rate of T-Ab in patients carrying CA + AA of -238G > A and -308G > A were notably higher in the OMG + TAO group than in the OMG group (both P<0.05) (Table 7). This evidence concerns the gene TNF and thromboangiitis obliterans.