POU3F2 and melanoma: Conversely, constitutive BRN2 overexpression was also performed in these same cell lines and revealed a commensurate increase in both NFIB (3.8, 3.7, 2.4 fold respectively) and EZH2 (2.5, 2.3, 2.6 fold respectively) expression across all three melanoma cell lines (Fig. 2B).