As BRN2 and MITF have been found to exhibit a predominantly inverse expression pattern in melanoma cells which promotes switching between invasive/migratory and proliferative phenotypes (Goodall et al., 2008, Hoek and Goding, 2010), we chose to examine the expression of BRN2, MITF and NFIB proteins in six melanoma cell lines. This evidence concerns the gene NFIB and melanoma.